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科学技术处副处长兼公共实验研究中心主任

江苏省“青蓝工程”优秀青年骨干教师,江苏省“六大人才高峰”高层次人才,江苏省“第五期333工程”第三层次。徐州医科大学优秀青年科技工作者。徐州医科大学第一届十大杰出青年。徐州市优秀共产党员。徐州市化学化工学会副理事长。学生心目中的好老师。淮海科学技术奖二等奖。主持国家自然科学基金,江苏省自然科学基金,江苏省高校自然科学基金等7项。在J. Am. Chem. Soc., Green Chem., Org. Lett., Chem. Eur. J., J. Org. Chem., Org. Chem. Front.等SCI刊物上发表多篇论文。授权发明专利4项,转让1项。主编、副主编、参编教材3部。Org. Lett., Org. Biomol. Chem., Scientific Reports, RSC Advances, Curr. Org. Chem.等杂志审稿人。

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团队成员
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代表性论文、专利
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1.Nan Wu, Chuang Li, Jiajia Mi, Yan Zheng, Zhou Xu*, A Strategy for Amide to β-Oxo Ester Transformation via N-Alkenoxypyridinium Salts as the Activator and H2O as the Nucleophile,Org. Lett.,2020, 22, 18, 7118–7122.

2.Ze-Shu Wang, Yang-Bo Chen, Kun Wang, Zhou Xu*, Long-Wu Ye*, One-pot synthesis of 2-hydroxymethylindoles via photoredox-catalyzed ketyl–ynamide coupling/1,3-allylic alcohol transposition,Green Chem.,2020, 22, 4483–4488.

3.Xueliang Zhou, Yuan Zhou, Qiang Zhu, Huimin Chen, Nan Wu, Xiangru Wen,Zhou Xu*,Synthesis of (1E, 3E)1,4diarylbuta1,3dienes promoted byμOMs palladium–dimer complex,BMC Chemistry,2019, 13, 39.

4.Xiaodong Tang, Nan Wu, Rongliang Zhai, Zheng Wu, Jiajia Mi, Renshi Luo,Zhou Xu*, Silver(I)-catalyzed addition of pyridine-N-oxides to alkynes: a practical approach for N-alkenoxypyridinium salts,Org. Biomol. Chem.,2019, 17, 966–972.

5.Rongliang Zhai, Yunsheng Xue, Ting Liang, Jiajia Mi,Zhou Xu*, Regioselective Arene and Heteroarene Functionalization: N-Alkenoxypyridinium Salts as Electrophilic Alkylating Agents for the Synthesis of α-Aryl/α-Heteroaryl Ketones.J. Org. Chem.2018,83(17), 10051–10059.

6.Zhou Xu*, Rongliang Zhai, Ting Liang, Liming Zhang,Efficient One-pot Multifunctionalization of Alkynes en Route to α- Alkoxyketones, α-Thioketones and α-ThioThioketals using an Umpolung Strategy,Chem. Eur. J.2017,23(57), 14133–14137.

7.Zhou Xu,*Ke Li, Rongliang Zhai, Ting Liang, Xiaodie Gui, Rongli Zhang, Efficient synthesis of benzene-fused 6/7-membered amides via Xphos Pd G2 catalyzed intramolecular C–N bond formation.RSC Advances,2017,82(7), 51972-51977.

8.Zhou Xu,Hongyi Chen, Zhixun Wang, Anguo Ying, Liming Zhang, One-Pot Synthesis of Benzene-Fused Medium-Ring Ketones: Gold Catalysis-Enabled Enolate Umpolung Reactivity,J. Am. Chem. Soc.2016, 138, 5515−5518.

9.Zhou Xu,*Yong Li, Jing Liu, Nan Wu, Ke Li, Songlei Zhu, Rongli Zhang and Yi Liu, Highly enantioselective asymmetric transfer hydrogenation (ATH) of α-phthalimide ketones,Org. Biomol. Chem.,2015,13(27), 7513-7516.

10.Zhou Xu,Hai Ren, Lijia Wang and Yong Tang,Efficient catalytic enantioselective Nazarov cyclizations of divinyl ketoesters,Org. Chem. Front.,2015, 2, 811-814.

11.徐洲、梁婷、米佳佳、翟荣良、石艳芬,中国发明专利,专利号:ZL202010314456.0,PF429242用于保护脑缺血再灌注损伤的医药用途,授权日期:202102月18日。

12.徐洲*、梁婷、米佳佳等,中国发明专利,一种醚类化合物的绿色高效合成方法,专利号:ZL201810182651.5,授权日期:202102月12日。

13.徐洲*等,中国发明专利,一种α-芳酮或α-杂芳酮的合成方法,专利号:ZL201810402652.6,授权日期:202102月10日,已转让。

14.徐洲*等,中国发明专利,一种蛋白酶抑制剂PF429242的合成方法,专利号: ZL 2012 1 0122280.4,授权日期:20148月06日。



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